I have to completely disagree with this point there Crackers.CrackTheSky wrote: It also doesn't help that a lot of the jokes require familiarity with the animes in question, so many of the jokes still go over my head. When it comes to comedy videos, my personal preference is that the jokes should not have to rely on any context outside the video itself.
This is an Anime music video meant to be shown to anime fans, and thus has anime related jokes in it.
Almost all jokes and humor require the audience's previous knowledge on some sort of subject for them to be funny. These ones just happen to require anime knowledge. Writing a joke that does not require the audience to have any sort of knowledge about the joke's subject would be near impossible. Humor pratically requires contextual knowledge.
It's kind of like saying "I don't like The Daily show because I don't understand who these politicians, or have no reference to these current events." Which is perfectly understandable, I mean if one had no knowledge of current American events, nor were they familiar with any politicians then the daily show would make little to no sense to them, this is however not the fault of the satirist.
So I guess, after typing that all out (which allowed me to work it out for myself) you are saying you don't like this video because you do not have the required knowledge to find the jokes amusing. Which is a fair complaint, but it's not against the video, nor the satirist. All this complaint is saying is you are not the appropriate audience.
Personally I don't believe that focusing your humor to a particular audience (be it "animu" or otherwise) is a bad thing.