moved to appropriate section.
Generally, the best thing you can do is to not let premiere do anything other than editing. Exporting uncompressed or with a lossless codec such as UTvideo, Lagarith or Huffyuv is recommended. When you do export, make sure the settings are the same as your project (resolution, field order, framerate, etc...).
From there you can compress that large file, that you'll get from premiere, with divx or xvid using virtualdub or something like it (or from the command line if you're so inclined). x264 offers better results than either divx or xvid, and Zarx264GUI can help you with that.
The amvapp should contain everything that you'll need for that. You can find it when you Read ErMaC & AbsoluteDestiny's Friendly AMV Guides Lovingly Overhauled Largely by Zarxrax