I did one of these for Final Fantasy games; it was loads of fun to make (but sucked as a product of course).
Pick your song well, something like this could go so many ways. Creepy, disturbing, violent, malicious, or comedic? (I went with malicious AND comedic, myself, based on the song.)
Anyhoo, keeping a theme and some common thread throughout instead of random shots of villains would also be something I wished I'd done.
Learn from my mistakes, heh.