YuruYuri would make for a good romcom, haha. You could have Kyoko as the main girl (she's blonde), and have the dude singing be Ayano. it would make a funny lesbian relationship.
I almost wanna say Escaflowne or Ouran Host Club. Hell, Excel Saga might work too, for that comedy/romantic take. Especially if ya go with an AMV Hell approach, and make it a short amv.