If you're unfamiliar with BitJazz's SheerVideo codec, it's worth a look. I replaced Animation/Uncompressed with Sheer a long time ago. A file that's ~25 GB in Uncompressed is ~7 GB in Sheer. The price for saving that much space LOSSLESSLY was worth keeping my desk free of yet another hard drive. For both Mac and Windows. There's a free fully functional tryout that lasts for a couple of weeks.
Normally $150, priced at $74.50 until January 14th.

